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目的:探讨鼻腔恶性黑色素瘤的临床特点及治疗。方法:对1997/2007年四川省肿瘤医院诊治的16例鼻腔恶性黑色素瘤病例资料进行回顾性分析。结果:本组病例中3例曾误诊为鼻咽癌,血管瘤和出血性息肉,误诊率为18.8%。11例死亡,死亡原因为局部复发(6例)和远处转移(5例)。结论:鼻腔恶性黑色素瘤恶性程度高,预后差。早期诊断和手术加术后放疗是有效治疗方法。
Objective: To investigate the clinical features and treatment of nasal malignant melanoma. Methods: The data of 16 cases of nasal malignant melanoma diagnosed and treated in Sichuan Cancer Hospital from 1997 to 2007 were retrospectively analyzed. Results: Three cases were misdiagnosed as nasopharyngeal carcinoma, hemangioma and hemorrhagic polyp in this group. The misdiagnosis rate was 18.8%. Eleven patients died, with local recurrences (6) and distant metastases (5). Conclusion: Malignant melanoma has high malignancy and poor prognosis. Early diagnosis and surgery plus postoperative radiotherapy is an effective treatment.