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目的探讨肌酸激酶同工酶(CK-MB)、心肌肌钙蛋白I(cTnI)和超敏C反应蛋白(hs-CRP)对儿童病毒性心肌炎的诊断价值。方法 42例病毒性心肌炎患儿作为观察组,42例健康儿童作为对照组,测定两组儿童的血清CK-MB,cTnI和hs-CRP。结果观察组患儿血清CK-MB,cTnI和hs-CRP均明显高于对照组(P<0.01)。观察组患儿CK-MB,cTnI,hs-CRP联合检测的灵敏性胃89.6%,特异性为94.6%,准确性胃92.7%,准确性明显高于单纯检测CK-MB、cTnI、hs-CRP(P<0.05)。结论联合检测CK-MB、cTnI和hs-crp可以更准确的诊断儿童病毒性心肌炎。
Objective To investigate the diagnostic value of CK-MB, cTnI and hs-CRP in children with viral myocarditis. Methods 42 children with viral myocarditis as observation group and 42 healthy children as control group, serum CK-MB, cTnI and hs-CRP were measured in two groups of children. Results The serum levels of CK-MB, cTnI and hs-CRP in the observation group were significantly higher than those in the control group (P <0.01). The sensitivity, specificity and accuracy of CK-MB, cTnI and hs-CRP in the observation group were 89.6%, 94.6% and 92.7% respectively, which were significantly higher than those of CK-MB, cTnI and hs-CRP (P <0.05). Conclusion Combined detection of CK-MB, cTnI and hs-crp can diagnose viral myocarditis in children more accurately.