论文部分内容阅读
目的探讨复方丹参注射液联合纳洛酮对新生儿缺氧缺血性脑病(HIE)疗效。方法 41例HIE患儿随机分为两组,对照组采用常规治疗,治疗组予复方丹参注射液联合纳洛酮治疗,观察疗效和NBNA评分。结果治疗组总有效率90%,明显优于对照组的84.3%(P<0.05);治疗组呼吸衰竭纠正时间、肌张力恢复时间、意识障碍恢复时间、原始反射恢复时间、惊厥控制时间明显低于对照组(P<0.05);治疗组出生后14d、28dNBNA评分明显高于对照组(P<0.05)。结论复方丹参注射液联合纳洛酮疗效明显,能较好改善机体神经功能。
Objective To investigate the curative effect of compound Danshen injection combined with naloxone on neonatal hypoxic-ischemic encephalopathy (HIE). Methods Forty-one children with HIE were randomly divided into two groups. The control group was treated by conventional therapy. The treatment group was given Salvia miltiorrhiza injection together with naloxone. The curative effect and NBNA score were observed. Results The total effective rate in the treatment group was 90%, which was significantly better than that in the control group (84.3%, P <0.05). The recovery time of respiratory failure, recovery time of muscle tone, recovery time of disturbance of consciousness, recovery time of primary reflex and convulsion control time in treatment group were significantly lower (P <0.05). The score of NBNA in the treatment group at 14d and 28d after birth was significantly higher than that in the control group (P <0.05). Conclusion Compound Danshen injection combined with naloxone has obvious curative effect, which can better improve the neurological function of the body.