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硝硫氰胺治疗日本血吸虫病临床上已广泛应用,治疗期间不少患者可有不同程度地出现神经精神方面的表现,但严重的神经精神反应尚缺乏报道,现将我们收治3例的情况摘要于下: 例一,硝硫氰胺所至亚急性联合变性患者女性,22岁,80年3月1日因粪检查出血吸虫卵在洱源县温水大队接受硝硫氰胺治疗(预计总剂量300毫克)。每次服50毫克,一天两次,当总量达250毫克时,出现严重头昏,次日自觉身体向右侧偏扭,不能控制,走路时向右侧倾倒,需他人扶助。至3月9日,右侧肢体不知疼痛,只晓冷热。在当地曾用细胞色素丙、肌苷、辅酶A、加兰他敏等治疗,病情无显著好转。于6月20日
Nitrocytosamine treatment of schistosomiasis japonica has been widely used in clinical practice, many patients may have varying degrees of neuropsychiatric performance during the treatment, but the serious neuropsychiatric response is still lack of coverage, now we receive 3 cases summary In the next: Example 1, subacute nitration of thiamine to subacute combined degeneration of female patients, 22 years old, March 1, 1980 due to fecal examination of schistosome eggs in Eryuan County, warm water brigade received nitriturine treatment (total expected dose 300 mg). Each serving of 50 mg twice a day, when the total amount of 250 mg, a serious dizziness, the next day conscious body to the right side of the twisted, uncontrollable, walking to the right dump, need help others. To March 9, I do not know the pain on the right limb, only know hot and cold. In the local cytochrome C, inosine, coenzyme A, galantamine and other treatment, the condition was not significantly improved. On June 20