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目的分析三维时间飞跃法MR血管成像(3D TOF MRA)检出颅内动脉瘤的价值。资料与方法 36例进行了3D TOF MRA且有数字减影血管造影(DSA)和/或手术结果为对照的患者纳入本研究。以DSA和/或手术结果为参照标准,以患者为分析单位评价3D TOF MRA检出颅内动脉瘤的能力。对3D TOF MRA均检出动脉瘤者,分别测量动脉瘤的长径、短径和瘤颈,进行相关性分析。结果 36例患者中DSA和/或手术检出28例患者有28个动脉瘤,8例患者无动脉瘤;3D TOF MRA检出31例患者31个动脉瘤,5例患者无动脉瘤。以DSA和/或手术结果为参照,以患者为分析单位,3D TOF MRA检出颅内动脉瘤的敏感性、特异性和准确性分别为89.3%、75.0%、75.0%。3D TOF MRA和DSA在显示颅内动脉瘤长径、短径和瘤颈的差别无统计学意义,并且有很好的正相关性。结论 3D TOF MRA在诊断颅内动脉瘤方面具有高的敏感性和中等的特异性,高的假阳性率提示在作出小动脉瘤的诊断时需谨慎。
Objective To analyze the value of three-dimensional time-of-flight MR angiography (3D TOF MRA) in detecting intracranial aneurysms. Materials and Methods 36 patients undergoing 3D TOF MRA with digital subtraction angiography (DSA) and / or surgical outcome as controls were included in this study. The ability of 3D TOF MRA to detect intracranial aneurysms was evaluated using the DSA and / or surgical results as a reference unit using the patient as the analysis unit. Aortic aneurysms were detected in 3D TOF MRA, and the long diameter, short diameter and neck of aneurysm were measured respectively. Results Twenty-eight aneurysms were detected in 28 of the 36 patients with DSA and / or surgery. There were no aneurysms in 8 patients, 31 aneurysms in 31 patients with 3D TOF MRA, and no aneurysms in 5 patients. The sensitivity, specificity and accuracy of 3D TOF MRA for detection of intracranial aneurysms were 89.3%, 75.0% and 75.0%, respectively, using DSA and / or surgical results as reference and patient as analysis unit. 3D TOF MRA and DSA in the intracranial aneurysms showed a long diameter, short diameter and tumor neck difference was not statistically significant, and there is a good positive correlation. Conclusions 3D TOF MRA has high sensitivity and medium specificity in the diagnosis of intracranial aneurysms. The high false positive rate suggests caution in the diagnosis of small aneurysms.