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目的:调研近3年来个体化药学服务在医院药学部门的开展情况。方法:选取2013年重点专科评审的89家医院作为研究对象,收集被调查医院2010-2012年期间个体化药学服务开展的品种、服务次数等指标的比较分析与评。结果与结论:近3年来,我国的个体化药学服务中治疗药物监测(TDM)项目平稳增长,基因检测项目发展迅速。虽然已有医院提供了根据基因型预处方,再结合TDM或其他监测指标进行调整的的个体化医疗服务,但对其可能造成药物代谢个体化差异的内外环境等因素还未给予足够的考虑,致使最终治疗效果仍不满意。
Objective: To investigate the implementation of individualized pharmacy services in the pharmaceutical department of the hospital in recent 3 years. METHODS: A total of 89 hospitals evaluated by key specialties in 2013 were selected as the research object to collect the comparative analysis and assessment of the varieties, service times and other indicators of individualized pharmacy services during the period from 2010 to 2012 in the investigated hospitals. RESULTS AND CONCLUSION: In the recent 3 years, the TDM project of personalized medicine service in our country has been steadily increasing, and the genetic testing programs have been developing rapidly. Although hospitals have provided individualized medical services based on genotype pre-prescriptions combined with TDM or other monitoring indicators, sufficient consideration has not been given to factors such as internal and external environments that may cause individual differences in drug metabolism. However, Resulting in the final treatment is still not satisfied.