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低T_3综合征是一种非甲状腺的疾病现象,它本身不是一种疾病,而是由疾病等情况引起的一种生化现象,其表现,患有各种系统性疾病的患者以及临床用某些药物的病例或各种原因引起的营养不良者,甲状腺本身功能正常,而血清总T_3浓度明显低于正常;总T_4浓度降低,但大多数情况下变动在正常范围内,在患者健康状况较严重的情况下可降低到正常范围以下;血清反T_3浓度极大多数高于正常,少数患者可正常或低于正常,其血清浓度的高低与当时的TT_4浓度或病情有关;血清TSH水平及TSH对TRH的反应在正常的稳定水平;血清FT_3和FT_4浓度一部分增高,一部分正常或降低,取决于疾病的种类和病情的轻重。这种现象实质上是外周甲状腺激素代谢异常,因此也有学者称之为“末梢性甲低”以区别于原发性和甲状腺本身原因造成的甲状腺功能低下。
Low T 3 syndrome is a non-thyroid disease phenomenon, which itself is not a disease, but by a disease caused by a biochemical phenomenon, the performance of patients with various systemic diseases and clinical use of certain Drugs or various causes of malnutrition, the thyroid itself is functioning properly, and serum total T 3 concentrations were significantly lower than normal; T 4 total concentration decreased, but in most cases the changes in the normal range, the more serious health conditions in patients Of cases can be reduced below the normal range; serum anti-T_3 concentrations were mostly higher than normal, a small number of patients may be normal or below normal, the level of serum concentration and the prevalence of TT_4 or disease; serum TSH levels and TSH TRH response in the normal level of stability; serum FT_3 and FT_4 concentration increased part of the normal or reduced, depending on the type of disease and the severity of the disease. This phenomenon is essentially peripheral abnormal thyroid hormone metabolism, so some scholars call it “distal hypothyroidism” to differentiate from the primary and thyroid itself causes hypothyroidism.