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目的了解福建省部分发热病例嗜肺军团菌感染情况,为军团菌病人群监测提供本底数据,也为流行病学研究提供依据。方法采集2008—2011年福建省3个设区市住院的部份发热患者血清,用酶联免疫吸附试验检测嗜肺军团菌抗体。结果采集标本140份,抗体阳性检出率9.2%。男性阳检率10.2%,女性7.7%;≤44岁、45～59岁和≥60岁抗体阳检率分别为8.5%、9.4%和10.2%。不同性别和年龄组的抗体阳检率均无统计学意义(P>0.05)。结论福建省3个设区市部分发热病例中存在嗜肺军团菌感染,需加强对军团菌病血清学监测,防止军团菌病发生。
Objective To understand the prevalence of Legionella pneumophila infection in some febrile cases in Fujian Province and to provide background data for the surveillance of Legionnaires’ disease population and to provide basis for epidemiological studies. Methods Serum of some febrile patients hospitalized in three districts of Fujian Province from 2008 to 2011 were collected, and antibodies against Legionella pneumophila were detected by enzyme linked immunosorbent assay (ELISA). Results 140 samples were collected, the positive rate of antibody was 9.2%. The positive rate of males was 10.2% and that of females was 7.7%. The positive rates of antibodies of ≤44, 45 ~ 59 and ≥60 were 8.5%, 9.4% and 10.2% respectively. There was no significant difference in the positive rate of antibody between different sexes and age groups (P> 0.05). Conclusion Legionella pneumophila infection exists in some febrile cases in three districts and districts in Fujian Province. Serological surveillance of Legionella pneumophila should be strengthened to prevent the occurrence of Legionnaires’ disease.