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目的探讨青少年女性卵巢上皮性肿瘤的临床病理特征及预后。方法收集1990年8月至2014年7月50例青少年卵巢上皮性肿瘤患者的临床病理资料。结果 50例患者平均发病年龄为(16.2±1.8)岁。月经来潮者占96.0%(48/50),单侧占90.0%(45/50),肿瘤直径>10 cm占73.0%(30/40)。病理类型主要为浆液性或黏液性卵巢肿瘤,其中黏液性占84.0%(42/50)。50例患者中,恶性占28.0%(14/50),交界性占34.0%(17/50),良性占38.0%(19/50)。14例卵巢癌中,Ⅰ期(FIGO 2009)9例,Ⅲ期4例,Ⅳ期1例。在48个月的中位随访期中,1例交界性肿瘤及2例ⅢC期卵巢癌患者失访,1例ⅢC期卵巢癌死亡,余患者均存活。结论青少年女性上皮性卵巢肿瘤诊断时分期较成年女性卵巢癌早,其预后较好。早期罹癌青少年女性接受保育手术是安全可靠的。
Objective To investigate the clinicopathological features and prognosis of adolescent ovarian epithelial tumors. Methods The clinical data of 50 cases of adolescent ovarian epithelial tumor from August 1990 to July 2014 were collected. Results The mean age of onset of the 50 patients was (16.2 ± 1.8) years. Menstrual cramps accounted for 96.0% (48/50), unilateral 90.0% (45/50), and tumor diameter> 10 cm accounted for 73.0% (30/40). Pathological types are mainly serous or mucinous ovarian tumors, of which 84% (42/50) of mucinous. Among the 50 patients, 28.0% (14/50) were malignant, 34.0% (17/50) were borderline, and 38.0% (19/50) were benign. In 14 cases of ovarian cancer, 9 cases of stage I (FIGO 2009), 4 cases of stage III and 1 case of stage IV. During a median follow-up of 48 months, one borderline tumor and two patients with stage IIIC ovarian cancer were lost to follow-up, and one patient died of stage IIIC ovarian cancer. All patients survived. Conclusions Adolescent female epithelial ovarian tumors have a better prognosis than those of adult women with ovarian cancer. Early cancer-bearing adolescent girls receiving childcare surgery is safe and reliable.