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目的探讨钛网修补术对未成熟颅骨后期生长情况的影响及相关因素分析。方法修补未发育成熟颅骨1年后,通过对形态学、病理学及脑容积的测量、骨及脑组织学检查等与正常组生长情况进行对照研究。结果对比两组头围的A、B、C三条线及脑容积,分别行统计学分析,结果P>0.05,认为无统计学意义。影像学及病理学检查示修补后的缺损区有明显的骨生长,生长方式有其特殊特点。结论临床医师应根据临床经验对小儿颅骨缺损可适当放宽手术适应证,早期行修补术。
Objective To investigate the effect of titanium mesh repair on immature skull late growth and related factors. Methods One year after the repair of immature mature skull, we compared the growth of the normal group with the morphological, pathological and brain volume measurement, bone and brain histological examination. Results The two groups of head circumference A, B, C three lines and brain volume were compared, respectively, statistical analysis, the results P> 0.05, that was not statistically significant. Imaging and pathological examination showed that the repaired defect area has obvious bone growth and its growth pattern has its own special characteristics. Conclusion Clinicians should be based on clinical experience in children with skull defects may be appropriate to relax surgical indications, early repair line.