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目的:为提高抢救重度有机磷农药中毒的成功率,观察血液灌流治疗重度有机磷农药中毒的疗效。方法:所有患者静注阿托品、解磷定及洗胃,治疗组同时用血液灌流(HP)治疗,血流150～200ml/min,首剂肝素1.0～1.5mg/kg,每小时追加10～15 mg,每个炭肾使用2～3小时。结果:治疗组出现阿托品化时间、平均住院时间、昏迷时间明显短于对照组(P<0.01);就诊时间在15小时之前,很少出现昏迷,并发症少。结论:HP能使重度有机磷农药中毒患者迅速清醒,达阿托品化时间、病死率、并发症发生率和住院时间明显减少,特别是早期就医的患者。
Objective: To improve the success rate of salvage severe organophosphorus pesticide poisoning, observe the curative effect of hemoperfusion on severe organophosphorus pesticide poisoning. Methods: All patients were treated with atropine, dephosphorization and gastric lavage. The treatment group was treated with hemoperfusion (HP) at the same time. The blood flow was 150 ~ 200ml / min and the first dose of heparin 1.0 ~ 1.5mg / kg. mg, each carbon kidney use 2 to 3 hours. Results: The treatment group showed atropistilization time, average length of hospital stay, and coma time significantly shorter than that of the control group (P <0.01). The treatment time was 15 hours, with few coma and few complications. Conclusion: HP can make patients with severe organophosphorus pesticide poisoning to wake up quickly, and the time, mortality, complication rate and length of hospital stay of daltepol significantly decrease, especially in the early stage of medical treatment.