论文部分内容阅读
1.研究背景:脑胶质瘤是成年人最常见的原发性脑肿瘤。目前标准的治疗方法通常是手术切除加术后辅助放射治疗。但疗效仍不理想,总的5年生存率为40%左右,尤其是胶质母细胞瘤疗效更差,通常不超过10%。以往采用合并亚硝基脲药物治疗,并观察到改善疗效的结果。新近开发的替莫唑胺是?
1. Background: Glioma is the most common primary brain tumor in adults. The current standard treatment is usually surgical resection plus postoperative adjuvant radiotherapy. But the effect is still not ideal, the overall 5-year survival rate was 40%, especially glioblastoma efficacy worse, usually not more than 10%. In the past with a combination of nitrosourea drug treatment, and to observe the results to improve the efficacy. What is the newly developed temozolomide?