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目的:评价糖皮质激素联合聚桂醇泡沫硬化剂治疗卡-梅综合征(现象)的临床疗效。方法:2013年1月—2014年12月间收治16例确诊的卡-梅综合征患儿,其中男7例,女9例;年龄最小5 d,最大1岁8个月,中位年龄3个月。瘤体位于头颈部8例,四肢6例,躯干部2例。16例患儿均首先采用静滴地塞米松注射液,0.5~0.75 mg/(kg·d),连用7 d,后改为口服泼尼松3~5 mg/(kg.d),隔天1次,晨起顿服,1个月后开始减量至停药;瘤体局部采用聚桂醇泡沫硬化剂注射治疗,每周1次,平均3~5次。治疗中密切观察患儿瘤体大小、硬度、色泽及温度变化,定期检测血小板计数。结果:随访6个月~2 a,痊愈10例,显效3例,无效3例,总有效率达81.3%。结论:糖皮质激素联合聚桂醇泡沫治疗卡-梅综合征疗效可靠,可明显降低激素的用量及服用时间,减少激素的副作用,易于推广应用。
Objective: To evaluate the clinical efficacy of glucocorticoids combined with lauromacrogol foam sclerotherapy in the treatment of card-May syndrome (symptom). Methods: From January 2013 to December 2014, 16 children with confirmed card-Mayer syndrome were admitted, including 7 males and 9 females. The youngest was 5 days and the oldest was 1 year and 8 months. The median age was 3 Months. Tumor located in the head and neck in 8 cases, limbs in 6 cases, 2 cases of trunk. All 16 patients were treated with intravenous injection of dexamethasone 0.5 ~ 0.75 mg / (kg · d) for 7 days, and then changed to 3 ~ 5 mg / (kg.d) for oral prednisone. The other day 1 times, morning meal Dayton clothing, 1 month after the start of dose reduction to discontinuation; tumor local use of lauromacrogol foam sclerotherapy, once a week, an average of 3 to 5 times. Closely observed in treatment of tumor size, hardness, color and temperature changes in patients with regular detection of platelet counts. Results: Followed up for 6 months to 2 years, 10 cases were cured, 3 cases were markedly effective, 3 cases were ineffective, and the total effective rate was 81.3%. Conclusion: Glucocorticoids combined with lauromacrogol treatment of card-Myzheimer syndrome is reliable and can significantly reduce the amount of hormone and taking time, reduce the side effects of hormones, easy to promote the application.