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为探讨内源性氧自由基损伤在口腔扁平苔藓（ＯＬＰ）发生发展过程中的作用，作者分别采用化学发光法和比色法对４２例ＯＬＰ患者组织中超氧化物歧化酶（ＳＯＤ）活性和过氧化脂质（ＬＰＯ）含量进行了研究。结果显示：①总体上看，ＯＬＰ组与正常组（３０例）相比，ＳＯＤ活性相差虽无统计学意义，但其均数是升高的，其中糜烂型（１４例）升高不如非糜烂型（２８例）明显；②ＯＬＰ组组织中ＬＰＯ含量及ＬＰＯ／ＳＯＤ比值与正常组相比差异不大；③糜烂型ＯＬＰ患者ＬＰＯ值、ＬＰＯ／ＳＯＤ比值均明显高于正常组和非糜烂型ＯＬＰ组；④非糜烂型ＯＬＰ组ＬＰＯ值较正常组降低。这些结果似可说明，在ＯＬＰ发生发展的不同阶段，ＳＯＤ和ＬＰＯ呈动态变化。
In order to investigate the role of endogenous oxygen free radical in the development of oral lichen planus (OLP), the author used chemiluminescence and colorimetric method respectively to detect the activity of superoxide dismutase (SOD) in 42 OLP patients Oxidative lipid (LPO) content was studied. The results showed that: ①Overall, OLP group compared with the normal group (30 cases), SOD activity difference was not statistically significant, but the average is increased, which erosive type (14 cases) increased as non-erosion (28 cases) were obvious; ② LPO content and LPO / SOD ratio in OLP group were not significantly different from normal group; ③ LPO value and LPO / SOD ratio in OLP patients were significantly higher than those in normal group and non-erosive OLP Group; ④ LPO in non-erosive OLP group was lower than that in normal group. These results may indicate that in the different stages of the development of OLP, SOD and LPO showed a dynamic change.