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近年来对药用植物的抗突变作用研究很多,发现这些植物依其作用大体可分五类:(1)降低突变、(2)杀菌作用、(3)增强突变、(4)既增强又降低突变、(5)无效。本文在Ames实验体系中用苯并(a)芘致突,考察了33种属于中医传统“扶正固本”或是具有自身稳定作用的药用植物,发现八种具有较强活性,可使突变降低95％以上。这八种植物药是芍药Paeonia 1actifolia、冷饭团Kadsura coccinea、白簕 Acanthopanax trifolia-tus、龙芽草 Agrimonia pilosa、金缨子 Rosa laevi-gata、黑面神 Breynia fructicosa、野鸦椿 Euscaphis japonica 和鸡血藤属植物 Millettia sp.另外还有9种植物可使突变下降80％～94％。而党参属植物可增强突变。在上述具有抗突变作用的植物中,有6种具有细胞毒性,即龙芽草、野鸦椿、长距淫
In recent years, there have been many studies on the antimutagenicity of medicinal plants, and it has been found that these plants can be roughly divided into five categories according to their effects: (1) reduction of mutations, (2) bactericidal action, (3) enhancement of mutations, (4) enhancement and reduction Mutation, (5) invalid. In this paper, the benzo(a) pyrene was used in the Ames experimental system to inspect 33 kinds of medicinal plants that belong to the traditional Chinese medicine “Fei Zheng Gu Ben” or have their own stabilizing effect. It was found that eight species have strong activity and can make mutations. Reduced by more than 95%. The eight botanical herbs are Paeonia lactifolia, Kadsura coccinea, Acanthopanax trifolia-tus, Agrimonia pilosa, Rosa laevi-gata, Breynia fructicosa, Eucalyptus japonica, and Millettia The genus Millettia sp. has 9 other plants that can reduce the mutation by 80% to 94%. Codonopsis plants can enhance mutations. Among the above-mentioned plants with antimutagenicity, 6 species are cytotoxic, ie, dragon bud grass, crow crow, long-distance kinky