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目前三叉神经痛的病因和发病机制尚未明确，导致临床上缺乏有效的治疗措施来解除三叉神经痛患者的口面部剧烈疼痛。理想的三叉神经痛动物模型是其发病机制研究的重要基础。近年来，基于三叉神经痛在临床治疗和基础研究中的重要发现，更多新颖实用的三叉神经痛动物模型被相继提出。这些动物模型具有各自的特点和优势，并分别适用于三叉神经痛发病机制的不同研究方向，从而有力推进了三叉神经痛病因及发病机制的研究进展。“,”The etiology and pathogenesis of trigeminal neuralgia is unclear, which causes the lack of effective therapeutic measures for the relief of the severe orofacial pain of patients with trigeminal neuralgia. Ideal animal models of trigeminal neuralgia are the important basis for studying of the pathogenesis of trigemi-nal neuralgia. Based on the key discoveries in clinical treatment and basic scientific research of trigeminal neuralgia,more novel and practical animal models of trigeminal neuralgia are put forward consecutively. With their own characteristics and superiorities,these animal models apply to different research aspects of the path-ogenesis for trigeminal neuralgia,boosting the development in the etiology and pathogenesis of trigeminal neu-ralgia.