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目的:观察热淋清颗粒联合注射用头孢噻肟钠治疗儿童尿路感染的临床疗效。方法:将120例尿路感染患儿随机分为观察组和对照组各60例。对照组单用头孢噻肟钠治疗,以100 mg/(kg·d)加入4∶1液100 m L中静脉滴注,每天2次;观察组给予热淋清颗粒联合头孢噻肟钠治疗,热淋清颗粒每天3次,每次4 g口服,头孢噻肟钠用法用量同对照组,观察记录患儿尿常规恢复正常时间、退热时间及治愈率。结果:观察组尿常规恢复正常时间、退热时间分别为(3.55±1.15)d、(1.75±0.68)d,短于对照组的(4.35±1.28)d、(2.41±0.94)d(P<0.05);观察组治愈率96.67%,高于对照组的85.00%(P<0.05)。结论:热淋清颗粒联合头孢噻肟钠治疗儿童尿路感染疗效优于单用头孢噻肟钠,且不良反应少,值得临床推广应用。
Objective: To observe the clinical effect of heat-clearing granule combined with cefotaxime sodium in the treatment of urinary tract infection in children. Methods: 120 cases of urinary tract infection were randomly divided into observation group and control group of 60 cases. The control group was treated with cefotaxime sodium only, 100 mg / (kg · d) was added to a 4: 1 solution of 100 m L by intravenous infusion twice a day. The observation group was given heat clearing granule combined with cefotaxime sodium treatment, Heat clearing granule 3 times a day, each 4 g oral administration of cefotaxime sodium dosage with the control group, observation of children with recurrent urinary routine time, antipyretic time and cure rate. Results: The urinary routine recovery time in the observation group was (3.55 ± 1.15) days and (1.75 ± 0.68) days, respectively, which was shorter than that in the control group (4.35 ± 1.28 days and 2.41 ± 0.94 days, P < 0.05). The cure rate in observation group was 96.67%, which was higher than that in control group (85.00%, P <0.05). Conclusion: The combination of Reizhen Granules and cefotaxime sodium in children with urinary tract infection is superior to cefotaxime sodium alone, with less adverse reactions, which is worthy of clinical application.