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漫性排斥反应是肾移植失败的主要原因。高滤过性（hyperfiltration）损害在移植肾慢性排斥反应发生发展过程中起重要作用[1]1肾移植高滤过性损害的基本概念高滤过性损害是指残留肾单位不足而引起肾脏血流动力学改变，以致形成肾小球滤过亢进和肾单位进一步丧失的恶性循环，最终
Diffuse rejection is the main reason for the failure of kidney transplantation. Hyperfiltration damage plays an important role in the development of chronic rejection of renal allografts [1] 1 The basic concept of hyperfiltration in renal transplantation Hyperfiltration damage refers to the deficiency of residual nephron causing renal blood Flow dynamics changed, resulting in the formation of glomerular filtration rate and renal cell loss further vicious circle, and ultimately