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目的探讨氯吡格雷预防冠心病介入治疗心血管的临床疗效。方法选取汝阳县人民医院收治的冠心病介入治疗疾病患者70例,根据治疗方法的不同,将其均分为试验组和对照组。其中对试验组患者采取氯吡格雷进行治疗,对照组患者采取噻氯吡啶治疗。比较两组患者治疗后不良反应出现率及治疗前后患者在不同时间段血小板出现聚集的情况。结果患者经治疗后血小板聚集率均呈现下降趋势,其中试验组血小板聚集率改善情况显著优于对照组患者;患者经治疗后病情均有好转,但对照组不良反应发生率显著大于试验组,两组比较差异有统计学意义(P<0.05)。结论氯吡格雷预防冠心病介入治疗心血管临床效果较好,血小板聚集率降低,安全性高,改善患者生活状态,恢复健康,值得普及实施。
Objective To investigate the clinical effect of clopidogrel in the prevention of cardiovascular intervention by coronary heart disease. Methods Seventy cases of coronary heart disease patients treated by Ruyang County People’s Hospital were selected and divided into experimental group and control group according to different treatment methods. The patients in the test group were treated with clopidogrel, while those in the control group were treated with ticlopyridine. The incidence of adverse reactions and the aggregation of platelets in patients at different time points before and after treatment were compared between the two groups. Results After treatment, the platelet aggregation rate showed a downward trend, in which the improvement of platelet aggregation rate in the experimental group was significantly better than that of the control group. The patients recovered after treatment, but the incidence of adverse reactions in the control group was significantly greater than that in the experimental group The difference was statistically significant (P <0.05). Conclusion Clopidogrel is effective in prevention of cardiovascular diseases due to interventional therapy of coronary heart disease. It is safe and effective to reduce the platelet aggregation rate, improve the life status and restore the health of patients.