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由于低能离子较低的组织穿透能力,其诱变机理一直是研究者争论的问题。近年来,本研究组的一系列研究工作已经证明在植物中存在辐射远程(诱变)效应,从一个新的角度解释了低能离子的诱变机理,然而依然无法解释低能离子辐照中的许多独特生物现象,而这些现象均具有明显的表观遗传学特性。以表观遗传学最具标志性特征的胞嘧啶甲基化为研究对象,以α粒子-拟南芥菜根辐照实验体系作为研究平台,检测了远程组织(器官)甲基化相关基因AtDML3的表达及特定基因片段的甲基化水平。研究证实,在植物个体水平辐射可以诱导远程表观遗传的变化,为进一步探索低能离子的诱变机理提供了新的思路。
Due to the low tissue penetration ability of low-energy ions, the mutagenesis mechanism has been the subject of debate. In recent years, a series of research work in this research group have demonstrated the long-range (mutagenic) effect of radiation in plants and explained the mutagenesis mechanism of low-energy ions from a new perspective. However, many of the low-energy ionizing radiation still can not be explained Unique biological phenomenon, and these phenomena have obvious epigenetic characteristics. In this study, cytosine methylation, the most landmark feature of epigenetics, was studied in this study. The α-particle-Arabidopsis root irradiation experiment system was used as a research platform to detect the expression of AtDML3 Expression and methylation level of specific gene fragments. Studies have confirmed that the level of plant epigenetic changes can induce long-range epigenetic changes in order to further explore the mechanism of mutagenesis of low-energy ions provides a new way of thinking.