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目的探讨临床药师在儿童重症监护病房抗感染药物治疗中的作用。方法通过临床药师参与1例感染性休克患儿抗感染药物治疗过程,与临床医师共同制订治疗方案,监护患者用药全过程,针对患者病情变化提出治疗方案调整。结果临床药师在抗感染治疗进程中,提出监测利奈唑胺血药浓度等建议被临床采纳,充分体现以药动学和药效学理论指导个体化给药。结论临床药师参与医疗团队,协助临床医师调整药物治疗方案,有利于提高药物治疗效果。
Objective To investigate the role of clinical pharmacists in anti-infective drug treatment in children’s intensive care unit. Methods By clinical pharmacists involved in 1 case of septic shock in children with anti-infective drug treatment process, together with the clinician to develop treatment programs, monitoring patients with the whole process of medication, the patient’s condition changes proposed treatment options. Results In the process of anti-infective therapy, clinical pharmacists proposed to monitor the lineal plasma concentration of linezolid and other clinical recommendations, fully demonstrating pharmacokinetic and pharmacodynamic theory to guide individualized administration. Conclusion Clinical pharmacists participate in the medical team to help clinicians adjust the drug treatment program, which is beneficial to improve the effect of drug treatment.