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目的探讨甲状腺功能正常的年轻人血清促甲状腺激素(TSH)水平与代谢综合征的关系。方法年轻志愿者216名,年龄18-40岁,TSH水平在正常范围(0.3-4.5mU/L)。以TSH>2.5mU/L作为上界参考值,分为高TSH组(A组,TSH 2.6-4.5mU/L,59例)和低TSH组(B组,TSH 0.3-2.5mU/L,157例)。分析两组患者TSH水平与代谢综合征的关系。结果 A组代谢综合征、中心性肥胖和高脂血症的发生率高于B组(13.6%vs.3.2%、23.7%vs.12.7%和11.9%vs.3.2%)(P<0.05)。收缩压、舒张压和甘油三酯水平与TSH水平呈正相关(P<0.05)。结论在TSH处于正常范围的健康年轻人群,TSH>2.5mU/L的个体应常规评估是否患有代谢综合征。
Objective To investigate the relationship between thyroid-stimulating hormone (TSH) and metabolic syndrome in young thyroid patients with normal function. Methods 216 young volunteers, aged 18-40 years old, TSH levels in the normal range (0.3-4.5mU / L). TSH> 2.5mU / L was taken as the reference value of the upper boundary and divided into high TSH group (group A, TSH 2.6-4.5mU / L, 59 cases) and low TSH group (group B, TSH 0.3-2.5mU / L, 157 example). The relationship between TSH levels and metabolic syndrome in both groups was analyzed. Results The incidence of metabolic syndrome, central obesity and hyperlipidemia in group A was higher than that in group B (13.6% vs.3.2%, 23.7% vs.12.7% and11.9% vs.3.2%, respectively) (P <0.05). Systolic blood pressure, diastolic blood pressure and triglyceride levels were positively correlated with TSH levels (P <0.05). Conclusion In healthy young people with normal TSH, individuals with TSH> 2.5 mU / L should be routinely assessed for metabolic syndrome.