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目的探讨盐酸氨溴索辅助治疗支气管肺炎的临床疗效。方法选取2013年9—12月在万安县高陂镇卫生院接受治疗的支气管炎患儿90例,随机分为对照组和观察组,各45例。对照组患儿在常规治疗的基础上加用溴己新祛痰进行辅助治疗;观察组患儿在常规治疗的基础上加用盐酸氨溴索进行辅助治疗。比较两组患儿治疗前后的血氧饱和度、呼吸频率等指标,以及药物不良反应发生情况。结果治疗前两组患儿呼吸频率和血氧饱和度比较,差异无统计学意义(P>0.05);观察组患儿治疗后的血氧饱和度高于对照组,呼吸频率慢于对照组,总有效率高于对照组,差异有统计学意义(P<0.05)。结论盐酸氨溴索注射液可改善支气管肺炎患儿临床症状,提高临床疗效,减少不良反应的发生。
Objective To investigate the clinical efficacy of ambroxol hydrochloride in the treatment of bronchial pneumonia. Methods Ninety children with bronchitis treated in Gaocheng Town Health Center, Wan’an County from September to December in 2013 were randomly divided into control group and observation group, with 45 cases in each group. Children in the control group were treated with bromhexine expectorant on the basis of routine treatment. Patients in the observation group received adjuvant therapy with ambroxol hydrochloride on the basis of routine treatment. The oxygen saturation, respiration rate and other indexes before and after treatment were compared between two groups of children and the incidence of adverse drug reactions. Results There was no significant difference in respiratory rate and oxygen saturation between the two groups before treatment (P> 0.05). The oxygen saturation of the observation group was higher than that of the control group, and the respiratory rate was slower than that of the control group. The total effective rate was higher than the control group, the difference was statistically significant (P <0.05). Conclusion Ambroxol hydrochloride injection can improve the clinical symptoms of children with bronchopneumonia, improve clinical efficacy and reduce the incidence of adverse reactions.