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目的：观察西沙比利对结肠镜检查术前肠道准备的影响。方法：患者４１６例，随机分为４组。Ⅰ～Ⅳ组肠道准备方法分别是：蓖麻油＋洗肠液；西沙比利片（西沙比利片１５ｍｇ，３次／ｄ，３ｄ）＋洗肠液；西沙比利片（西沙比利片１５ｍｇ，３次／ｄ，１ｄ）＋洗肠液；西沙比利片（西沙比利片１０ｍｇ，３次／ｄ，３ｄ）＋蓖麻油＋洗肠液。结果：４种肠道准备方法肠道清洁率无显著性差异，但Ⅱ、Ⅲ组方法腹痛发生率明显高于Ⅰ、Ⅳ组。Ⅰ、Ⅳ组中便秘患者的肠道清洁率，Ⅳ组明显高于Ⅰ组。结论：非便秘患者Ⅰ组肠道准备方法较适宜，而便秘患者Ⅳ的肠道准备方法较适宜，西沙比利可以提高便秘患者肠道清洁度。
Objective: To observe the effect of cisapride on intestinal preparation before colonoscopy. Methods: 416 patients were randomly divided into 4 groups. The intestinal preparation methods of group Ⅰ ~ Ⅳ were: castor oil + washing intestinal fluid; cisapride tablets (15mg Sisalibili tablets, 3 times / d, 3d) + intestinal fluid; cisapride tablets 3 times / d, 1d) + cleansing solution; cisapride tablets (cisapride tablets 10mg, 3 times / d, 3d) + castor oil + cleansing liquid. Results: There was no significant difference in intestinal cleanness among the four intestinal preparation methods, but the incidence of abdominal pain in group Ⅱ and group Ⅲ was significantly higher than that in group Ⅰ and Ⅳ. Intestinal tract clearance in patients with constipation in group Ⅰ and Ⅳ was significantly higher than that in group Ⅳ. Conclusion: The intestine preparation method of group Ⅰ is more suitable for non-constipation patients, while the intestine preparation method Ⅳ of constipation patients is more appropriate. Cisapride can improve the intestinal tract cleanness of constipation patients.