论文部分内容阅读
目的了解2010—2013年辽宁省辽阳市手足口病病原学特征,为手足口病的预防和控制提供科学防控依据。方法收集2010—2013年疑似手足口病病例粪便标本,应用RT-PCR方法进行核酸检测;采用SPSS 16.0软件进行统计分析。结果 2010年采集标本121份,检测阳性为106份(87.60%),其中EV71阳性31份(29.25%),Cox A16阳性45份(42.45%),其他肠道病毒阳性30份(28.30%);2011年采集标本120份,检测阳性为104份(86.67%),其中EV71阳性26份(25%),Cox A16阳性32份(30.77%),其他肠道病毒阳性46份(44.23%);2012年采集标本242份,检测阳性为197份(81.40%),其中EV71阳性65份(32.99%),Cox A16阳性92份(46.70%),其他肠道病毒阳性40份(20.30%);2013年采集标本360份,检测阳性为301份(83.61%),其中EV71阳性4份(1.33%),Cox A16阳性199份(66.11%),其他肠道病毒阳性98份(32.56%)。结论 Cox A16为辽阳市2010—2013年手足口病的优势病原体,其他肠道病毒所占比例占检测样本总数的25.39%,应加强对其进一步分型检测。
Objective To understand the etiological characteristics of HFMD in Liaoyang City of Liaoning Province from 2010 to 2013 and provide scientific basis for prevention and control of HFMD. Methods Stool specimens suspected of hand-foot-mouth disease were collected from 2010 to 2013, and the nucleic acid was detected by RT-PCR. SPSS 16.0 software was used for statistical analysis. Results A total of 121 samples (87.60%) were detected in 2010, of which 31 (29.25%) were positive for EV71, 45 (42.45%) were positive for Cox A16 and 30 (28.30%) were positive for other enteroviruses. In 2011, 120 samples were collected, of which 104 were positive (86.67%), of which 26 (25%) were positive for EV71, 32 (30.77%) were positive for Cox A16 and 46 (44.23%) were positive for other enteroviruses. Of 242 samples collected in the year, 197 were positive (81.40%), of which 65 were EV71 positive (32.99%), 92 were Cox A16 positive (46.70%) and 40 were other positive enterovirus (20.3%). The positive samples were collected from 360 samples, of which 83 were positive (83.61%), of which 4 (1.33%) were positive for EV71, 199 (66.11%) were positive for Cox A16 and 98 (32.56%) were positive for other enteroviruses. Conclusion Cox A16 is the dominant pathogen of hand-foot-mouth disease in Liaoyang City from 2010 to 2013. The proportion of other enteroviruses accounted for 25.39% of the total samples tested. Cox A16 should be further tested for its typing.