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慢肝、肝硬化患者,神经内分泌系统的激活在病程进展中发挥重要作用。本研究检测慢肝、肝硬化患者肾素-血管紧张素-醛固酮系统(RAAS)各激素水平的变化,探讨循环血RAAS的变化在慢性肝炎、肝硬化发生、发展过程中的作用。1 资料与方法1.1 临床资料 观察组54例为诊断明确的慢性乙型肝炎、肝硬化患者,符合中华医学会传染病与寄生虫分会、肝病学分会2000年9月修订的诊断标准,男31例,女23例;年龄20～72岁,平均45.8岁。包括慢性肝炎24例,肝硬化30例,其中25例行肝组织穿刺活检。对照组22例为健康查体正常者,已排除心、
Slow liver, cirrhosis patients, neuroendocrine system activation plays an important role in the course of the disease. This study was designed to examine the changes of various hormone levels in the renin-angiotensin-aldosterone system (RAAS) of patients with chronic liver cirrhosis and cirrhosis and to explore the role of changes in RAAS in the pathogenesis of chronic hepatitis and cirrhosis. 1 Materials and Methods 1.1 clinical data observed in 54 cases of patients with clear diagnosis of chronic hepatitis B, cirrhosis patients, in line with the Chinese Medical Association of Infectious Diseases and Parasites Branch, liver disease credits will be revised in September 2000 diagnostic criteria, 31 males , 23 females; aged 20 to 72 years, mean 45.8 years old. Including 24 cases of chronic hepatitis, liver cirrhosis in 30 cases, of which 25 cases of liver biopsy. Control group, 22 cases of normal physical examination, have ruled out the heart,