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50例有颈部包块的间变癌(anaplastic carcinoma),均经免疫细胞化学证实,并排除了分化不良的鳞癌、无黑色素的色素瘤及非何杰金淋巴瘤。30人能找到原发灶(A组),其中25人在头颈部(鼻咽腔14、口咽5、甲状腺3、上颌窦1、口底1、筛窦1)。20人找不到原发灶(B组)。男∶女=2∶1。平均年龄,男50.3岁,女54.5岁。A组的颈部淋巴结包块63%位于上半颈部;而B组47%位于上颈部。以放射疗法为主。A组有20%、B组有50%的人未接受治疗。但二组2年存活率无明显差别,均为30%左右;因此在找不到原发灶时,对其怀疑部位进行治疗是不必要的。预后与年龄、全身状况、原发肿瘤分期有关,与性
Fifty cases of anaplastic carcinoma with cervical mass were confirmed by immunocytochemistry, and poorly differentiated squamous cell carcinoma, pigmented melanoma, and non-Hodgkin’s lymphoma were excluded. Thirty people were able to find the primary lesion (group A), of which 25 were in the head and neck (nasopharyngeal cavity 14, oropharynx 5, thyroid 3, maxillary sinus 1, floor 1 and ethmoid 1). Twenty people could not find the primary tumor (Group B). Male: female = 2:1. The average age is 50.3 years old and 54.5 years old. In the A group, 63% of the cervical lymph node mass was located in the upper half of the neck; 47% of the B group was located in the upper neck. Radiation therapy is the mainstay. 20% of patients in group A and 50% of patients in group B received no treatment. However, there was no significant difference in the two-year survival rate between the two groups, which were all around 30%; therefore, when the primary tumor cannot be found, it is not necessary to treat the suspected site. The prognosis is related to age, general condition, primary tumor stage, and sex