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乳癌确诊时有腋淋巴结转移是其远期预后的最准确指标。随着乳腺筛检计划的问世,检诊出的可保守治疗的小乳癌的比例日益增多,但对其淋巴结状况往往不了解。用螺旋样香膏型植物血凝素(Helix Poma-tia lectin,HPA)标记原发性乳癌的石蜡切片标本,能检测出糖基的变化,作者研究了这一变化与腋淋巴结转移之间的关系。1967年～1972年作者所在医院手术切除原发性乳癌373例,其中290例术中已知淋巴结情况,随访19～24年,收集其他可
Axillary lymph node metastasis at the time of diagnosis of breast cancer is the most accurate indicator of its long-term prognosis. With the advent of breast screening programs, the proportion of small breast cancers that can be conservatively treated is increasing, but lymph node status is often not known. Helical Poma- tia lectin (HPA) was used to mark paraffin-embedded specimens of primary breast cancer to detect changes in glycosyl groups. The authors studied this change and axillary lymph node metastasis. relationship. From 1967 to 1972, the author’s hospital had 373 cases of primary breast cancer resection, of which 290 were known to have lymph node status during the operation and were followed up for 19 to 24 years.