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目的比较奥曲肽与生长抑素治疗肝硬化食道静脉破裂出血的临床效果。方法通过对2009年4月至2014年11月进行治疗的476例肝硬化食道静脉破裂出血患者进行分组,其中对照组患者给予奥曲肽治疗,实验组患者实施生长抑素治疗。观察比较两组患者的止血效果和不良反应差异。结果实验组患者的有效止血率为84.46%,不良反应发生率为8.82%,对照组患者的有效止血率为86.55%,不良反应发生率为7.98%,两组止血效果和不良反应发生率比较无显著性差异(P>0.05)。结论针对肝硬化食道静脉破裂出血患者采用奥曲肽或生长抑素均有较好的临床效果。
Objective To compare the clinical efficacy of octreotide and somatostatin in the treatment of cirrhosis with esophageal venous hemorrhage. Methods 476 patients with cirrhosis and esophageal variceal bleeding were divided into groups treated with octreotide from April 2009 to November 2014. The patients in the control group were treated with somatostatin. Observed and compared the two groups of patients with hemostatic effects and adverse reactions. Results In the experimental group, the effective hemostasis rate was 84.46% and the adverse reaction rate was 8.82%. The effective hemostatic rate in the control group was 86.55% and the adverse reaction rate was 7.98%. There was no significant difference between the two groups in the rate of hemostasis and adverse reactions Significant difference (P> 0.05). Conclusion The clinical efficacy of octreotide or somatostatin in cirrhotic patients with esophageal variceal hemorrhage has a good clinical effect.