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氯喹抗药性的逆转研究提示多重抗药性疟原虫和肿瘤细胞之间存在相似性,某些钙拮抗剂、吩噻嗪、钙调蛋白抑制剂和三环类抗抑郁药可以通过抑制药物外流而逆转抗药
Reversal of chloroquine resistance suggests that there is a similarity between multidrug-resistant Plasmodium and tumor cells and that certain calcium antagonists, phenothiazine, calmodulin inhibitors and tricyclic antidepressants may be reversed by inhibiting drug efflux Resistant