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多囊卵巢综合征(PCOS)多用克罗米芬(CC)诱发排卵,一些作者报道的排卵率为76%,而妊娠率为33%,hMG为其主要的替代治疗药物,其排卵率约79~95%,妊娠率为28%,而自然流产率,多胎妊娠和过度刺激的发生率相当高,并发症的出现与hMG中含有LH有关。本文对用纯FSH治疗PCOS的临床效果与hMG对比。观察49例PCOS妇女均有典型的症状体征,曾接受过CC治疗,最大剂量为200mg/日×5天,至少三个周期无排卵,随机接受FSH和hMG治
Polycystic ovary syndrome (PCOS) with clomiphene citrate (CC) induced ovulation, some authors reported an ovulation rate of 76%, while the pregnancy rate was 33%, hMG as its main alternative treatment, the ovulation rate of about 79 ~ 95 %, The pregnancy rate was 28%, while the incidence of spontaneous abortion, multiple pregnancies and over-stimulation of the very high incidence of complications associated with hMG LH. In this paper, the clinical effect of pure FSH in the treatment of PCOS compared with hMG. 49 cases of PCOS were observed in women with typical symptoms and signs, had received CC treatment, the maximum dose of 200mg / day × 5 days, at least three cycles of anovulation, randomized to receive FSH and hMG