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在所有正常成人中都有少量(<1%)胎儿血红蛋白(HbF)。应用特殊的抗HbF抗体进行免疫荧光研究证明这种HbF分布在0.2～7%的红细胞中,这些细胞称为F细胞。通过单细胞免疫扩散测定HbF/F细胞的含量表明HbF约占血红蛋白含量的30%,其余为HbA。在一些血液学正常的成人中发现HbF少量增加,HbF呈不均一分布的特点,包括遗传性胎儿血红蛋白持续存在综合征(HPF-H)瑞士型和英国型,并且统一归类为“杂
Small (<1%) fetal hemoglobin (HbF) is present in all normal adults. The use of special anti-HbF antibody for immunofluorescence studies have shown that this HbF distribution in 0.2 to 7% of red blood cells, these cells are called F cells. Determination of HbF / F cell mass by single-cell immunodiffusion indicated that HbF accounted for about 30% of the hemoglobin content and the balance was HbA. HbF was found to be slightly increased in some hematologically normal adults and was heterogeneously distributed in HbF, including the hereditary fetal hemoglobin persistence syndrome (HPF-H) Swiss type and the British type, and was categorized as "heterozygote