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本形态测定研究是通过对孕16～18周有血浆AFP升高而无羊水AFP升高的单胎妊娠的胎盘进行检查,观察是否从胎盘可以得到母体血浆AFP升高的解释。收集10例在产前筛查中母体血浆AFP升高(多于中位数2倍)但无羊水AFP升高的胎盘。AFP是在孕16～18周测量的,超声检查未见胎儿畸形,除血浆AFP升高外无合并症,无先兆流产、高血压或糖尿病也无产前出血。其婴儿在新生儿期没有
This morphometric study examines the placenta of singleton pregnancies with elevated AFP in plasma from 16 to 18 weeks of gestation, and observes whether an increase in maternal plasma AFP can be obtained from the placenta. Ten placentas were collected from 10 males with elevated AFP (more than 2-fold median) in prenatal screening but without elevated amniotic fluid AFP. AFP is measured at 16 to 18 weeks’ gestation and no fetal malformations were seen on sonography. No complications were found except elevated plasma AFP, and no threatened abortion, high blood pressure, or no prenatal bleeding in diabetes. The baby does not have it during the newborn period