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本文用肠腔灌注和原子吸收光谱分析法测定了6例内源性皮质醇增多症病人空肠对钙和镁的吸收功能。结果与同性别、年龄近似的6例正常对照者比较差异无显著性,空肠钙吸收分别为:-7.89±2.72、-12.50±6.17mg·h~(-1)/30cm(P>0.05);镁吸收分别为-4.47±7.41、+1.61±3.60mg·h~(-1)/30cm(P>0.05)。本组病人与正常组相比较,尿钙排量增多,血钙降低,血浆iPTH增高。初步讨论了这些改变与本病并发骨质疏松的关系。
In this paper, the intestinal absorption of calcium and magnesium in jejunum of 6 patients with endogenous cortisol hypersecretion were determined by intestinal perfusion and atomic absorption spectrometry. The results showed that there was no significant difference between the same sex and age 6 normal controls. The calcium absorption in jejunum was -7.89 ± 2.72, -12.50 ± 6.17 mg · h -1 and 30 cm, respectively (P> 0.05). The magnesium absorption was -4.47 ± 7.41 and + 1.61 ± 3.60 mg · h -1 / 30 cm, respectively (P> 0.05). This group of patients compared with the normal group, increased urinary calcium excretion, decreased serum calcium, plasma iPTH increased. Preliminary discussion of these changes and the disease complicated with osteoporosis.