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目的 :探讨血清铜蓝蛋白氧化酶 (sCP)活性变化与妇科肿瘤的关系。方法 :采用联大茴香胺酶比色法测定良性肿瘤 30例、恶性肿瘤 47例、恶性肿瘤根治术后 12例及正常对照组 12 5名女性的血清sCP活性。结果 :恶性肿瘤患者sCP活性明显高于良性肿瘤患者、行根治术后的恶性肿瘤患者及正常对照组 (P <0 .0 1) ;而良性肿瘤患者、行根治术后的恶性肿瘤患者及正常对照组sCP活性之间差异无显著性 (P >0 .0 5 )。结论 :sCP活性检测对于妇科良性和恶性肿瘤的鉴别诊断有一定价值 ,且可作为观察恶性肿瘤患者病情变化的重要生化指标。
Objective: To investigate the relationship between changes of serum ceruloplasmin oxidase (sCP) activity and gynecological tumors. Methods: The serum sCP activity of 30 women with benign tumors, 47 patients with malignant tumors, 12 patients with malignant tumor after radical operation and 125 normal controls were measured by the method of anisodamine synthase assay. Results: The sCP activity in patients with malignant tumors was significantly higher than that in patients with benign tumors, patients with malignant tumors after radical operation and the normal control group (P <0.01); while patients with benign tumors underwent radical surgery and normal There was no significant difference in sCP activity between the two groups (P> 0.05). Conclusion: The detection of sCP activity has certain value in the differential diagnosis of benign and malignant tumors of gynecology, and it can be used as an important biochemical indicator to observe the changes of patients with malignant tumors.