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作者对315例HBV感染引起的肝炎、肝硬变进行了细胞角蛋白 19(cytokeratin 19,CK19)和CK18的ABC免疫组化研究。结果表明,110例慢性肝炎中80例(73％)及144例肝硬变和早期肝硬变中117例(81％)有肝细胞CK异常表达(即肝细胞表达“胆管型”CK);它可作为慢性活动性肝炎与慢性迁延性肝炎及各型慢性活动性肝炎之间的区分和肝硬变活动性判定的辅助指标,是慢性肝病活动性的表现,特别与碎屑状肝细胞
The author of 315 cases of HBV infection caused by hepatitis, cirrhosis cytokeratin 19 (cytokeratin 19, CK19) and CK18 ABC immunohistochemistry. The results showed that in 110 cases of chronic hepatitis (73%) and 144 cases of cirrhosis and early cirrhosis, 117 cases (81%) had abnormal expression of hepatocytes (ie, hepatocytes express “bile duct” type CK). It can serve as a secondary indicator of the distinction between chronic active hepatitis and chronic persistent hepatitis and various types of chronic active hepatitis and determination of cirrhosis activity is the manifestation of chronic liver disease activity, especially with dendritic cells