Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice

来源 :世界胃肠病学杂志：英文版 | 被引量 : 0次 | 上传用户：cr15mo3

【摘要】

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AIM To clarify the roles of TWEAK and its receptor Fn14 in 5-fluorouracil(5-FU)-induced diarrhea.METHODS Diarrhea was induced in wild-type(WT), Fn14 knockout(KO

【作者】

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Takuhito Sezaki Yuki Hirata Te

【机构】

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DepartmentofGastroenterology,ResearchCenterforHepatitisandImmunology,2~（nd）DepartmentofInternalMedic

【出处】

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世界胃肠病学杂志：英文版

【发表日期】

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2017年13期

【关键词】

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癌症化疗 INTERLEUKIN-13 INTERLEUKIN-33 Interleukin-13 受体 2 Cancer chemotherapy Inte

【基金项目】

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Supported by the Grants-in-Aid for Scientific Research,No.[B]5H04503 and No.[C]25460965,No.16K09299 from the Ministry of Education,Culture,Sports,Science,and Technology,the National Center for Global

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AIM To clarify the roles of TWEAK and its receptor Fn14 in 5-fluorouracil(5-FU)-induced diarrhea.METHODS Diarrhea was induced in wild-type(WT), Fn14 knockout(KO), and IL-13 receptor(IL-13R)α1 KO BALB/c mice using a single injection of 5-FU. Histological a

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Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice

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