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  5. hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma

hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma

来源 :世界胃肠病学杂志：英文版 | 被引量 : 0次 | 上传用户：txzhang50
【摘 要】
：
AIM To screen clinically relevant micro RNAs (mi RNAs) silenced by DNA methylation in human hepatocellular carcinoma(HCC).METHODS Knockdown of DNA methyltransfe
【作 者】
：
Sumadi Lukman Anwar Till Krech 
【机 构】
：
UlrichLehmann,DepartmentofSurgery,DepartmentofGastroenterology,InstituteofHumanGenetics
【出 处】
：
世界胃肠病学杂志：英文版
【发表日期】
：
2017年9期
【关键词】
：
hsa-miR-183 DNA methylation DNMT 击倒 microRNA microarray hsa-miR-183  DNA methyla 
【基金项目】
：
Supported by the Deutsche Forschungsgemeinschaft,No.(DFG) SFB-TRR77 “Liver cancer”(Project B1)
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AIM To screen clinically relevant micro RNAs (mi RNAs) silenced by DNA methylation in human hepatocellular carcinoma(HCC).METHODS Knockdown of DNA methyltransferases (DNMTs) using si RNAs and mi RNA profiling in HCC cell lines were performed to identify D
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