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目的:观察经阴道彩超引导下介入治疗未破裂型异位妊娠的临床效果,为未破裂异位妊娠的临床治疗提供一种新的途径。方法:观察经阴道彩超引导下局部注射氨甲蝶呤治疗未破裂型异位妊娠22例患者(A组)术后不同阶段的血β-HCG值、包块的大小及成功率,并与同期行肌肉注射药物治疗的23例患者(B组)的相同资料进行对比分析。结果:经方差分析,两组治疗后同阶段复查的血β-HCG、超声复查包块大小变化为P<0.05,提示A组β-HCG下降、恢复至正常值时间及包块缩小时间均优于B组。两组的成功例数经χ2检验,P值均小于0.05。结论:经阴道彩超介入治疗是一种微创、高效、安全的治疗未破裂异位妊娠的方法,比肌注药物治疗能取得更好的疗效,在病例选择的适应证、治疗的成功率以及预防胚囊破裂等方面有明显的优势。
Objective: To observe the clinical effect of transvaginal ultrasound-guided interventional treatment of unruptured ectopic pregnancy and to provide a new approach for the clinical treatment of unruptured ectopic pregnancy. Methods: The blood β-HCG, the size of the mass and the success rate of different stages of post-operation in 22 patients with unruptured ectopic pregnancy undergoing transvaginal ultrasound-guided methotrexate treatment were observed and compared with the same period The same data from 23 patients treated with intramuscular drug therapy (group B) were compared. Results: After analysis of variance, the change of mass of β-HCG in the same stage after the treatment of two groups was P <0.05, which indicated that the β-HCG of group A decreased, the time of recovery to normal and the time of shrinkage were both excellent In group B Two groups of successful cases by χ2 test, P values ?? were less than 0.05. Conclusion: Transvaginal ultrasound is a minimally invasive, efficient and safe method for the treatment of unruptured ectopic pregnancy, and can achieve better efficacy than intramuscular drug treatment. The indications of the cases, the success rate of treatment and Prevention of blastocyst rupture and other areas have obvious advantages.