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The behayiors of 4-aryl-1 (2H)-phthalazinones (1a-c)toward carbon nucleophiles (Grignardreagents) and secondary amine under Mannich conditions as well as the nucleophilic substitution reactionon chlorophthalazine derivatives have been studied.
The behayiors of 4-aryl-1 (2H) -phthalazinones (1a-c) toward carbon nucleophiles (Grignardreagents) and secondary amine under Mannich conditions as well as the nucleophilic substitution reaction of chlorophthalazine derivatives have been studied.