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目的前瞻性研究透明角膜切口白内障超声乳化术后泪膜及眼表的变化。方法选取连续就诊手术的白内障惠者共36例44眼,分为两组,A组为术前存在干眼症患者,共7例9眼;B组为术前无干眼症患者,共29例35眼。两组患者均行上方透明角膜切口超声乳化术联合后房型折叠式人工晶状体植入术。分别于术前第1d,术后第2d、第5d、第10d、第30d进行干眼症相关症状调查、无麻醉下泪液分泌试(Schirmer试验SIt)、泪膜破裂时间(break-up time,BUT)、角膜荧光素染色检查并积分(corneal fluorescein staining,sta),比较各项结果在术后不同时间与术前的差异以及手术对两组患者影响程度的差异。结果两组患者分别与术前比较,术后不适主诉增加。Schirmer试验值在术后第2d和第5d明显高于术前,BUT在术后第2d、第5d和第10d较术前缩短,角膜荧光素染色积分在术后第2d、第5d高于术前。差异均有显著性(P<0.05)。结论白内障超声乳化术可在短期内影响患者的泪膜和眼表。
Objective To prospectively study the changes of tear film and ocular surface after phacoemulsification with clear corneal incision. Methods A total of 36 eyes (36 eyes) with cataract who were treated by continuous operation were divided into two groups. Group A was preoperatively with dry eye syndrome, a total of 7 cases (9 eyes). In group B, there were 29 cases without dry eye before surgery 35 eyes. Transparent corneal incision phacoemulsification combined with posterior chamber foldable intraocular lens implantation was performed in both groups. The symptoms of dry eye were investigated on the first day before operation, the second day, the fifth day, the tenth day and the thirtieth day after operation, respectively. The symptoms of dry eye syndrome such as schirmer test (SIt), break-up time (BUT), corneal fluorescein staining (sta). The difference of the results between the postoperative time and the preoperative time and the effect of the operation on the two groups of patients were compared. Results The two groups of patients were compared with preoperative, postoperative discomfort increased. The Schirmer test value was significantly higher than that before operation on the 2nd and 5th postoperative day, and the BUT shortened at the 2nd, 5th and 10th day after operation. The score of corneal fluorescein staining was higher at 2 and 5 days after operation before. The difference was significant (P <0.05). Conclusions Cataract phacoemulsification can affect the patient’s tear film and ocular surface in a short period of time.