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目的:评价硝呋太尔制霉素阴道软胶囊用于治疗霉菌性阴道炎患者的临床疗效与安全性。方法:选取2014年6月—2015年12月间诊治的霉菌性阴道炎患者82例,将其分为对照组40例和观察组42例;对照组患者均采用达克宁栓治疗,观察组患者则给予硝呋太尔制霉素阴道软胶囊局部给药治疗,比较两组患者治疗后的总有效率及不良反应的发生情况。结果:观察组患者治疗后的总有效率为97.62%,高于对照组为75.00%(P<0.05);治疗结束后1月内随访患者,观察组患者复发率低于对照组(P<0.05);两组患者不良反应的发生率经比较其差异无统计学意义(P>0.05)。结论:采用硝呋太尔制霉素阴道软胶囊治疗霉菌性阴道炎患者的疗效优于达克宁栓,其治疗效果较显著,可降低复发率。
Objective: To evaluate the clinical efficacy and safety of nifuratel nystatin vaginal soft capsules in the treatment of patients with fungal vaginitis. Methods: Totally 82 patients with mycotic vaginitis who were diagnosed and treated between June 2014 and December 2015 were divided into control group (n = 40) and observation group (n = 42). Patients in the control group were treated with metoclopramide and those in observation group Give nifuratel nystocin vaginal soft capsules for local administration, the two groups of patients after treatment compared the total efficiency and adverse reactions. Results: The total effective rate in observation group was 97.62%, which was higher than that in control group (75.00%, P <0.05). The recurrence rate in observation group was lower than that in control group after one month follow-up ). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion: Nifuratel nystatin vaginal soft capsules in the treatment of fungal vaginitis in patients with superior efficacy than dacron suppository, the treatment effect is more significant, can reduce the recurrence rate.