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为了探讨卵巢恶性生殖细胞肿瘤的临床特点、治疗和预后,回顾性分析22例卵巢恶性生殖细胞肿瘤患者的临床资料。22例患者均行手术治疗,13例患者手术时保留了生育功能,20例患者术后辅以BEP和BVP等方案化疗,随访至2009-12-31,3例失访,2例死亡,其余患者无复发及转移,截至随访结束仍然无瘤生存,2年和5年生存率均为89.5%(17/19)。回顾性分析结果提示,卵巢恶性生殖细胞肿瘤患者术后辅以BEP或BVP为主的化疗,治疗疗效较好;对侧卵巢和子宫正常的患者,可行保留生育功能手术,而对于晚期患者采用保留生育功能手术要慎重。
In order to explore the clinical features, treatment and prognosis of malignant ovarian germ cell tumors, the clinical data of 22 patients with malignant ovarian germ cell tumors were analyzed retrospectively. Twenty-two patients were treated surgically. Thirteen patients retained fertility at the time of surgery. Twenty patients received postoperative chemotherapy such as BEP and BVP. Follow-up was from 2009 to December 31, 3 were lost to follow-up and 2 died. The rest The patients had no recurrence and metastasis, and they remained tumor-free by the end of follow-up. The 2-year and 5-year survival rates were 89.5% (17/19). Retrospective analysis of the results suggest that patients with malignant ovarian germ cell tumors after surgery supplemented with BEP or BVP-based chemotherapy, the treatment effect is good; contralateral ovary and uterine normal patients, feasible to retain reproductive function surgery, and for advanced patients with retention Fertility surgery to be careful.