Changes of Ghrelin/GOAT axis and m TOR pathway in the hypothalamus after sleeve gastrectomy in obese

• 作 者: Qiang Wang Wei Tang Wen-Sheng
• 机 构: DepartmentofGeneralSurgery,DepartmentofSurgery
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2017年34期
• 关键词: GHRELIN Ghrelin O-acyltransferase Type-2 糖尿病 视下丘 肥胖 袖子 gastrectomy rapamycin 的哺乳
• 基金项目: Supported by the National Natural Science Foundation of China,No.81270969(to Wei Zhang)and No.81300723(to Cheng-Xiang Shan),,Shanghai Science and Technology Commission,No.12ZR1439100(to Wei Zhang)

AIM To examine the changes of the ghrelin/ghrelin O-acyltransferase(GOAT) axis and the mammalian target of rapamycin(m TOR) pathway in the hypothalamus after sleeve gastrectomy.METHODS A total of 30 obese type-2 diabetes Sprague-Dawley(SD) rats, 6 wk of a