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铁粒幼细胞性贫血具有如下特征:呈低色素性贫血(有时为正色素性或高色素性)、血清铁增高、骨髓幼红细胞增生并出现许多特殊形态的铁粒幼细胞——“环状”铁粒幼细胞、铁代谢呈无效造血以及发生血色病等。临床表现先天性型除个别病例外均发生于男性。获得性原发性病例男女两性无明显差别,根据Kushner等的统计,男女之比为1.5∶1,男性稍多。发病年龄除先天性型外多见于中年以后,作者等观察的病例在50—59岁之间。起病缓慢,多由于贫血的症状而就医,极少数患者有皮肤光线过敏和色素沉着等主诉。
Myeloid leukocyte anemia has the following characteristics: hypochromic anemia (sometimes positive or hyperpigment), elevated serum iron, bone marrow erythroid hyperplasia and the emergence of many special forms of iron granulocyte - “ring ”Iron granulocyte, iron metabolism was ineffective hematopoiesis and hemochromatosis and so on. Clinical manifestations of congenital except in a few cases occurred in men. Acquired primary cases There was no significant difference between men and women, according to Kushner and other statistics, the ratio of male to female 1.5: 1, slightly more men. In addition to the onset of onset of age more common in middle age, the authors observed cases between 50-59 years old. Slow onset, mostly due to the symptoms of anemia and medical treatment, a very small number of patients with skin light allergies and hyperpigmentation and other complaints.