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离体大鼠心脏灌流模型的实验表明，牛磺酸除明显减轻再灌注心肌的钙超载和脂质过氧化外，还显著改善心肌肌浆网（ＳＲ）的钙转运功能，牛磺酸使肌浆网的钙─三磷酸腺苷酶活性较缺血／再灌注组升高１．１１倍，摄钙初速率和最大摄钙量分别升高６１．７±１．１％和４０．９±６．４％。牛磺酸可直接拮抗氧自由基灌流导致的心肌细胞和ＳＲ的损伤，对离休ＳＲ无直接作用，对心肌局部的肾素─血管紧张素系统也未见有影响。研究结果显示，牛磺酸的心肌保护作用还与其降低再灌注时心肌的脂质过氧化有关。
In vitro rat heart perfusion model experiments showed that taurine in addition to significantly reduce reperfusion myocardial calcium overload and lipid peroxidation, but also significantly improve myocardial sarcoplasmic reticulum (SR) calcium transport function, taurine muscle The calcium-ATPase activity of the pulp network was 1.11 times higher than that of the ischemia / reperfusion group, and the initial and maximum calcium uptake rates were increased by 61.7 ± 1.1% and 40.9 ± 6.4, respectively %. Taurine can directly antagonize the oxygen free radicals perfused cardiomyocytes and SR damage, has no direct effect on the SR, but also on the local myocardial renin-angiotensin system. The results showed that the myocardial protection of taurine is also related to its ability to reduce myocardial lipid peroxidation during reperfusion.