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目的观察双歧杆菌四联活菌片联合蒙脱石散治疗小儿轮状病毒性肠炎的疗效。方法选择2010年8月至2012年12月在本院住院的162例诊断为轮状病毒性肠炎患儿,随机分为观察组和对照组,观察组92例,对照组70例,两组患儿均给予合理补液纠正水电解质紊乱、利巴韦林抗病毒,及进食指导等基础治疗,观察组在此基础上加用双歧杆菌四联活菌片、蒙脱石散,治疗期间观察两组患儿大便次数、性状、有无呕吐及脱水情况,以及有无不良反应。结果观察组总有效率90.22%,对照组为74.29%,χ2=7.26,P<0.05,差异有统计学意义,且未发现明显不良反应。结论双歧杆菌四联活菌片联合蒙脱石散对轮状病毒性肠炎有较好的治疗作用,且无明显不良反应,值得临床推广。
Objective To observe the curative effect of Bifidobacterium quadricepsis combined with montmorillonite in treating children rotavirus enteritis. Methods 162 cases diagnosed as rotavirus enteritis in our hospital from August 2010 to December 2012 were randomly divided into observation group and control group, 92 cases in observation group and 70 cases in control group Children were given a reasonable rehydration to correct water and electrolyte disorders, ribavirin antivirals, and eating guidance and other basic treatment, the observation group on the basis of the use of live Bifidobacterium quadriceps tablets, montmorillonite powder, observed two during treatment Group stool frequency, traits, with or without vomiting and dehydration, and with or without adverse reactions. Results The total effective rate was 90.22% in the observation group, 74.29% in the control group, χ2 = 7.26, P <0.05, the difference was statistically significant, and no obvious adverse reactions were found. Conclusion Bifidobacterium quadriceps could effectively treat rotavirus enteritis with montmorillonite powder, and no obvious adverse reactions, worthy of clinical promotion.