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口服剂型胰岛素既方便患者也乐于服用。为了使主药有效地进入血液循环，必须克服胃、小肠内的活性蛋白水解酶破坏及上皮细胞阻止大分子物质输送至血液的过筛效应。本文报道了采用包衣技术，配方中加入表面活性物质和蛋白水解酶抑制剂，制成新的口服剂型胰岛素，可降低血中葡萄
Oral dosage form of insulin is also easy to take patients. In order for the primary drug to effectively enter the blood circulation, it is necessary to overcome the disruption of active proteolytic enzymes in the stomach and intestine and the screening effect of the epithelial cells against the transport of macromolecular substances to the blood. This article reports the use of a coating technique that adds a surfactant and a protease inhibitor to the formulation to make a new oral dosage form of insulin that reduces blood glucose