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HLA是迄今发现的最复杂的人类遗传标记,具有高度多态性。由于用传统的淋巴细胞毒试验检验HLA分型,对检材要求很高,因此很难应用于法医学领域中。随着分子生物学技术的迅猛发展,HLA分型已深入到基因水平。国内陆续研究报道了应用PCR一特异性寡核着酸探针(SSOP)及PCR-单链
HLA is by far the most complex human genetic marker found, with a high degree of polymorphism. Due to the traditional lymphocyte cytotoxicity test to test the HLA typing, the requirements of the detection of high, it is difficult to apply in the field of forensic science. With the rapid development of molecular biology technology, HLA typing has been deep into the genetic level. Domestic studies have reported the use of a PCR-specific oligonucleotide probe (SSOP) and PCR-single-stranded