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目的观察布地奈德联合特布他林雾化吸入治疗儿童支气管(BA)哮喘的临床效果。方法选取医院收治的儿童BA患者120例作为研究对象,随机分为观察组和对照组,每组60例。对照组采用特布他林雾化吸入治疗,观察组在对照组基础上联合布地奈德治疗,观察2组患儿临床效果、治疗前后第1秒用力呼气量(FEV_1)、最大呼气流量(PEF)的变化及不良反应发生情况。结果观察组治疗总有效率为95.00%,高于对照组的81.67%(P<0.05)。治疗后,2组FEV_1、PEF数值均改善,且观察组FEV_1、PEF效果优于对照组(P<0.01)。观察组不良反应发生率为3.33%,低于对照组的15.00%(P<0.05)。结论在儿童支气管哮喘的治疗中联合布地奈德和特布他林雾化吸入治疗能够提升治疗效果和安全性,改善患者的呼吸功能,值得临床推广应用。
Objective To observe the clinical efficacy of budesonide and terbutaline in nebulization for bronchial asthma in children. Methods A total of 120 children with BA in our hospital were selected as study subjects and randomly divided into observation group and control group with 60 cases in each group. The control group was treated with inhalation of terbutaline. The observation group was treated with budesonide on the basis of the control group. The clinical effects, the forced expiratory volume at 1 second (FEV 1), the maximum expiratory flow rate (PEF) changes and adverse reactions. Results The total effective rate of the observation group was 95.00%, which was higher than that of the control group (81.67%, P <0.05). After treatment, the FEV_1 and PEF values in both groups were improved, and the FEV_1 and PEF effects in the observation group were better than those in the control group (P <0.01). The incidence of adverse reactions in the observation group was 3.33%, which was lower than that in the control group (15.00%, P <0.05). Conclusions The combination of budesonide and terbutaline in the treatment of children bronchial asthma can improve the therapeutic effect and safety and improve the respiratory function of patients. It is worthy of clinical application.